Challenge: Protocol Design
Question Number 1

Which of the following would be classed as surrogate endpoints?

1) Time to death

2) Reduction in LDL cholesterol

3) Increase in specific antibody level in testing a new vaccine

4) Relief of pain at 2 hours post dose
A
1 only
B
1 and 2 only
C
2 and 3 only
D
3 and 4 only

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